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This town took its name from the Spanish word for rawhides--cuero (KWER-o)--because Native Americans often salvaged animal hides along a local creek notorious for trapping cattle. Once a round-up point on the Chisholm Trail, the town was a true "Wild West" outpost. Today, many historic buildings remain, with more than 50 structures and homes listed as recorded Texas historic landmarks or in the National Register of Historic Places. Contact the visitor center for driving tour information.
Cuero is the seat of DeWitt County, which was designated the "Wildflower Capital of Texas" by the Texas Legislature. Maps with routes for wildflower viewing are available each April.
The Guadalupe River offers fishing and river paddling opportunities, with three official put-in sites on a Texas Paddling Trail. Cuero also is on the Great Texas Coastal Birding Trail.
Events include the Texas River Marathon and the Turkeyfest Celebration on the second full weekend of October.